Tumor-draining lymph node (TDLN) lymphocytes contain immunologically sensitized to tumor but functionally deficient T cells. The 30 kDa protein, antigen, a major secreted protein antigen of Mycobacterium tuberculosis, exhibits strong T cell
stimulatory
T cell stimulatory effect. In this study, it examined that the feasibility of using M. tuberculosis 30 kDa antigen to antigen to stimulate tumor-draining lymph node cells for the generation of specific immune effector cells.
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